POLYMORPHISM OF ARTEMISININ FROM ARTEMISIA-ANNUA

Authors
CHAN KL YUEN KH TAKAYANAGI H JANADASA S PEH KK
Citation
Kl. Chan et al., POLYMORPHISM OF ARTEMISININ FROM ARTEMISIA-ANNUA, Phytochemistry, 46(7), 1997, pp. 1209-1214
Citations number
12
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
46
Issue
7
Year of publication
1997
Pages
1209 - 1214
Database
ISI
SICI code
0031-9422(1997)46:7<1209:POAFA>2.0.ZU;2-N
Abstract
X-ray crystallography studies have confirmed the discovery of a new po lymorphic artemisinin crystal belonging to the triclinic space group, P1. The physicochemical properties of the new polymorph have been comp ared with those of the previously known orthorhombic P2(1)2(1)2(1) cry stal by microscopic examination, density measurements, differential sc anning calorimetry, infrared spectroscopy and dissolution studies. (C) 1997 Elsevier Science Ltd.