POTENTIAL OF CAPILLARY ELECTROPHORESIS WITH MICELLES OR CHIRAL ADDITIVES AS A PURITY CONTROL METHOD IN PHARMACEUTICAL-INDUSTRY

Authors
RIEKKOLA ML WIEDMER SK
Citation
Ml. Riekkola et Sk. Wiedmer, POTENTIAL OF CAPILLARY ELECTROPHORESIS WITH MICELLES OR CHIRAL ADDITIVES AS A PURITY CONTROL METHOD IN PHARMACEUTICAL-INDUSTRY, Process control and quality, 10(1-2), 1997, pp. 169-180
Citations number
52
Journal title
Process control and quality → ACNP
ISSN journal
09243089
Volume
10
Issue
1-2
Year of publication
1997
Pages
169 - 180
Database
ISI
SICI code
0924-3089(1997)10:1-2<169:POCEWM>2.0.ZU;2-E
Abstract
This review looks at the potential of capillary electrophoresis (CE) w ith micelles or chiral selectors for the determination of drug related impurities and the monitoring of optical and chiral selector purity. The major benefits of CE over high performance liquid chromatography a re high efficiency, fast and low-cost analysis, small sample volumes, and low reagent consumption. (C) 1997 Elsevier Science B.V.