This article reviews laryngeal cleft, anomalies from the Laryngeal Dev
elopment Laboratory at Children's Memorial Hospital in Chicago and inc
ludes a discussion of the classification of laryngotracheoesophageal c
lefts based on previous work and the information presented herein. Of
the 115 laryngeal specimens obtained between 1975 and 1995, 11 have la
ryngeal cleft anomalies. Eight have a submucous laryngeal cleft. There
is 1 laryngotracheoesophageal cleft, type II (partial cricoid cleft);
and there are 2 laryngotracheoesophageal clefts, type III (complete c
ricoid cleft). The histopathologic findings are presented in detail an
d the literature is reviewed. Photomicrographs and drawings illustrate
the pathology and classification. Clinical presentation, diagnosis, e
valuation, and management are discussed, as is the embryology.