INTRONS ENABLE THE POLYOMAVIRUS MIDDLE AND SMALL T-ANTIGENS TO STIMULATE THE GROWTH OF PRIMARY RAT EMBRYO FIBROBLASTS

Authors
ASSELIN C SULLIVAN M BASTIN M
Citation
C. Asselin et al., INTRONS ENABLE THE POLYOMAVIRUS MIDDLE AND SMALL T-ANTIGENS TO STIMULATE THE GROWTH OF PRIMARY RAT EMBRYO FIBROBLASTS, Gene, 203(2), 1997, pp. 175-181
Citations number
36
Categorie Soggetti
Genetics & Heredity
Journal title
Gene → ACNP
ISSN journal
03781119
Volume
203
Issue
2
Year of publication
1997
Pages
175 - 181
Database
ISI
SICI code
0378-1119(1997)203:2<175:IETPMA>2.0.ZU;2-3
Abstract
We constructed spliceable vectors that separately encode polyomavirus MT and ST. The addition of an intron enables MT to transform and to im mortalize more efficiently and ST to transiently stimulate the growth of primary rat embryo fibroblasts. (C) 1997 Elsevier Science B.V.