PREMARKET EVALUATION OF A COMMERCIAL GLYCOPROTEIN G-BASED ENZYME-IMMUNOASSAY FOR HERPES-SIMPLEX VIRUS TYPE-SPECIFIC ANTIBODIES

Authors
ASHLEY RL WU LX PICKERING JW TU MC SCHNORENBERG L
Citation
Rl. Ashley et al., PREMARKET EVALUATION OF A COMMERCIAL GLYCOPROTEIN G-BASED ENZYME-IMMUNOASSAY FOR HERPES-SIMPLEX VIRUS TYPE-SPECIFIC ANTIBODIES, Journal of clinical microbiology, 36(1), 1998, pp. 294-295
Citations number
22
Categorie Soggetti
Microbiology
Journal title
Journal of clinical microbiology → ACNP
ISSN journal
00951137
Volume
36
Issue
1
Year of publication
1998
Pages
294 - 295
Database
ISI
SICI code
0095-1137(1998)36:1<294:PEOACG>2.0.ZU;2-Q
Abstract
A new commercial glycoprotein G-based enzyme immunoassay (gG-EIA) was compared with Western blotting (WE) for detection of herpes simplex vi rus type 1 (HSV-1) or HSV-2 type specific antibodies in 193 serum samp les. Sensitivity for HSV-1 was 95%; specificity was 96%. Sensitivity f or HSV-2 was 98%; specificity was 97%. Twelve of 13 serum samples with equivocal gG-EIA results were serotyped by WB.