Js. Ross et al., THE POSTOPERATIVE LUMBAR SPINE - EVALUATION OF EPIDURAL SCAR OVER A 1-YEAR PERIOD, American journal of neuroradiology, 19(1), 1998, pp. 183-186
Citations number
18
Categorie Soggetti
Clinical Neurology","Radiology,Nuclear Medicine & Medical Imaging
PURPOSE: We documented the morphological changes on enhanced MR imagin
g studies that occur in epidural scar over a period of 1 year after lu
mbar diskectomy.METHODS: The study population was culled from a random
ized, multicenter clinical trial designed to evaluate the efficacy of
a device inhibiting postoperative epidural fibrosis after single-level
, unilateral laminectomy/diskectomy for herniated lumbar disk. Analysi
s was restricted to 71 control subjects who did not receive the device
. All patients underwent surgery after receiving clinical and MR exami
nations, with follow-up MR studies at 6 and 12 months. Evaluation of a
ll MR images was performed by one interpreter, who was blinded to trea
tment arm and clinical findings. The extent of epidural scar seen at t
he 6- and 12-month MR examinations was graded on a scale of 0 to 4 for
each quadrant at each imaging section encompassing the surgical level
. RESULTS: Eighty-five percent of the patients had no change in the am
ount of anterior epidural scar between the 6- and 12-month MR examinat
ions; 75% of the patients showed no change in the amount of posterior
epidural scar between the 6- and 12-month examinations. CONCLUSION: Th
e majority of our patients had no change in the amount of epidural sca
rring visible at enhanced MR imaging over a 1-year period after lumbar
laminectomy/diskectomy.