CLINICAL AND MORPHOLOGICAL ASPECTS OF LARYNGEAL CYSTS

To our knowledge only a few defined studies have been carried out on l aryngeal cysts. These cysts represent a mixed group of benign laryngea l lesions that can cause diagnostic and therapeutic difficulties. The aim of this study was to characterize their histological structure and localizations in the larynx as well as to discuss theories about thei r genesis. Between 1973 and 1996, 342 laryngeal cysts were treated at Phillips University of Marburg, while from 1990 to 1996, 74 were treat ed at Justus Liebig University of Giessen. In all, 416 laryngeal cysts were treated by endolaryngeal microsurgery. All clinical charts were reviewed retrospectively and surgical specimens examined histomorpholo gically. Findings showed that 58.2% of the laryngeal cysts were locate d in the glottic area and 18.3% in the ventricular folds. The remainde r were located on the aryepiglottic fold (2.2%) and interarythenoid re gion (0.7%). Two congenital cysts were also treated. Approximately 56% of the laryngeal cysts were lined by squamous cell epithelium, 37% by respiratory epithelium and 7% by oncocytic epithelium. Zn general, th e laryngeal cysts were found to be a collection of inhomogenous lesion s from different histogenetic origins with diverse symptoms related to their site and size. On the basis of our investigations, a new classi fication was established concerning the genesis and development of lar yngeal cysts by subdividing cysts into congenital cysts, retention cys ts, and inclusion cysts.