METASTATIC CARCINOMA OF UMBILICUS - SISTER-MARY-JOSEPHS-NODULE

A 72-year-old woman presented with a progressively enlarging, painful umbilical nodule, A biopsy specimen of the lesion showed focally mucin -producing adenocarcinoma, and the patient was diagnosed to have metas tatic carcinoma of umbilicus: Sister Mary Joseph's nodule, Search for the primary tumor revealed adenocarcinoma of the splenic flexure of co lon with metastasis to liver, spleen, and periaortic lymph nodes, Sist er Mary Joseph's nodule is a well-known entity, It is a rare form of c utaneous umbilical metastases, can present as the first sign of intra- abdominal malignancy, carries very poor prognosis, and generally is in operable, This report emphasizes the need for careful evaluation of an y umbilical lesion and the importance of histologic diagnosis in case of doubt.