Evidence for one or more loci on the human X chromosome influencing so
cial cognition was recently presented by Skuse ef al.((1)). The imprin
ted locus is only expressed from a paternally inherited X chromosome,
which means that boys do not express it because their only X chromosom
e comes from their mother. This raises the possibility of genetic as w
ell as cultural influences on sex differences in behaviour and cogniti
on. It may also offer some explanation for why boys are more vulnerabl
e to developmental disorders that affect social behaviour, such as aut
ism.