MODELING AND SIMULATION OF MULTICOMPONENT NONLINEAR CHROMATOGRAPHY

Citation
R. Zenhausern et Dwt. Rippin, MODELING AND SIMULATION OF MULTICOMPONENT NONLINEAR CHROMATOGRAPHY, Computers & chemical engineering, 22(1-2), 1998, pp. 259-281
Citations number
37
Categorie Soggetti
Computer Science Interdisciplinary Applications","Engineering, Chemical","Computer Science Interdisciplinary Applications
ISSN journal
00981354
Volume
22
Issue
1-2
Year of publication
1998
Pages
259 - 281
Database
ISI
SICI code
0098-1354(1998)22:1-2<259:MASOMN>2.0.ZU;2-2
Abstract
The equilibrium relationship between the stationary and the mobile pha se plays a leading role in chromatography; especially for higher conce ntrations where the equilibrium relationship becomes nonlinear. Based on local equilibrium theory, a simple numerical algorithm is developed by considering the multicomponent nonlinear equilibrium relationship and its Jacobian matrix to quickly obtain a first prediction of the ch romatographic separation without the need of providing mass transfer d ata. The impact of several favorable multicomponent equilibrium isothe rms on chromatographic separations is studied: The multicomponent Lang muir isotherm, a polynomial and an exponential extension of the multic omponent Langmuir isotherm. (C) 1997 Elsevier Science Ltd.