The hemodynamic consequences of a pneumoperitoneum are well understood
, but there have been no studies investigating its impact on splanchni
c mucosal perfusion. By use of nasogastric tonometry, this study demon
strates that fit patients undergoing elective laparoscopic cholecystec
tomy at normal pneumoperitoneum pressures (12-15 mm Hg) develop signif
icant splanchnic mucosal ischemia. This is a particular concern in pat
ients with preexistent peripheral vascular disease undergoing prolonge
d laparoscopic procedures.