ASYMMETRIC-SYNTHESIS OF ALKYLARYLCARBINOLS VIA REACTION OF A CHIRAL PINANEDIOL ALKYLBORONIC ESTER WITH ARYLMETHYL CHLORIDES

Authors
KABALKA GW LI NS YU S
Citation
Gw. Kabalka et al., ASYMMETRIC-SYNTHESIS OF ALKYLARYLCARBINOLS VIA REACTION OF A CHIRAL PINANEDIOL ALKYLBORONIC ESTER WITH ARYLMETHYL CHLORIDES, Tetrahedron : asymmetry, 8(23), 1997, pp. 3843-3846
Citations number
28
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
8
Issue
23
Year of publication
1997
Pages
3843 - 3846
Database
ISI
SICI code
0957-4166(1997)8:23<3843:AOAVRO>2.0.ZU;2-T
Abstract
The reaction of arylmethyl chlorides with chiral pinanediol esters of alkylboronic acids in the presence of lithium dicyclohexylamide afford s chiral alkylarylcarbinols in good stereochemical yields after oxidat ion. (C) 1997 Elsevier Science Ltd. All rights reserved.