ACYCLIC NUCLEOSIDE TRIPHOSPHATE ANALOGS AS TERMINATORS IN BIOCATALYTIC DNA-REPLICATION

Authors
MARTINEZ CI ANSARI MA GIBBS R BURGESS K
Citation
Ci. Martinez et al., ACYCLIC NUCLEOSIDE TRIPHOSPHATE ANALOGS AS TERMINATORS IN BIOCATALYTIC DNA-REPLICATION, Bioorganic & medicinal chemistry letters, 7(23), 1997, pp. 3013-3016
Citations number
7
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
23
Year of publication
1997
Pages
3013 - 3016
Database
ISI
SICI code
0960-894X(1997)7:23<3013:ANTAAT>2.0.ZU;2-U
Abstract
The acyclic nucleoside triphosphates 1 and 2 were prepared and tested as substrates for several DNA replicating enzymes; AmpliTaq(R) FS and Taquenase(R) accepted these compounds as substrates leading to chain t ermination. (C) 1997 Elsevier Science Ltd.