Eb. Mazo et al., THE SELECTIVE ALPHA-BLOCKER ALFUZOSIN IN THE TREATMENT OF BENIGN PROSTATIC HYPERPLASIA, Terapevticeskij arhiv, 69(10), 1997, pp. 79-82
40 patients with benign prostatic hyperplasia (BPH) were treated with
the alpha-blocker alfuzosin which was administered per os twice a day
in a dose 5 mg. The treatment brought about a decrease of the mean sym
ptom score from 19.6 to 12.2, of quality of life from 5.2 to 2.1, of r
esidual urine from 152 to 82 ml. Mean and maximal urinary flow rates r
ose by 35 and 45%, respectively. The level of prostate-specific antige
n over the treatment course did not change. The findings of the trial
evidence for high efficacy of alfuzosin in the treatment of urination
disorders in BPH patients.