D. Reisman et al., ANESTHETIC EFFICACY OF THE SUPPLEMENTAL INTRAOSSEOUS INJECTION OF 3-PERCENT MEPIVACAINE IN IRREVERSIBLE PULPITIS, Oral surgery, oral medicine, oral pathology, oral radiology and endodontics, 84(6), 1997, pp. 676-682
Objective, To determine the efficacy of a supplemental intraosseous in
jection of 3% mepivacaine in mandibular posterior teeth with irreversi
ble pulpitis. Intraosseous injection pain, subjective heart rate incre
ase, and pain ratings during endodontic treatment were also assessed.
Study Design, Forty-eight patients with irreversible pulpitis received
conventional inferior alveolar nerve blocks. Electric pulp testing wa
s used to determine pulpal anesthesia. Patients who were positive to t
he pulp testing, or negative to pulp testing but felt pain during endo
dontic treatment, received an intraosseous injection of 1.8 ml of 3% m
epivacaine. A second intraosseous injection of 3% mepivacaine (1.8 mi)
was given if the first injection was unsuccessful. Results, Seventy-f
ive percent of patients required an initial intraosseous injection bec
ause of Failure to gain pulpal anesthesia. The inferior alveolar block
was 25% successful; the first intraosseous injection increased succes
s to 80%. A second intraosseous injection further increased success to
98%. These differences were significant (p < 0.05). Eight percent (4/
48) of the initial intraosseous injections resulted in solution being
expressed into the oral cavity; these were considered technique failur
es. Conclusions, For mandibular posterior teeth with irreversible pulp
itis, a supplemental intraosseous injection of 3% mepivacaine increase
d anesthetic success. A second intraosseous injection, when necessary,
further improved success.