Le. Reinstein et al., PREDICTING OPTICAL DENSITOMETER RESPONSE AS A FUNCTION OF LIGHT-SOURCE CHARACTERISTICS FOR RADIOCHROMIC FILM DOSIMETRY, Medical physics, 24(12), 1997, pp. 1935-1942
Various forms of GAFChromic (GC) film have been used for several years
as radiographic media for measuring dose distributions of brachythera
py sources and small radiation fields. In order to optimize the measur
ement sensitivity and thus improve precision, we describe a method to
calculate the dose response curves (net optical density at a give wave
length or spectrum versus absorbed dose) for different densitometer li
ght sources using measured GC him absorption spectra. Comparison with
measurements on the latest version of GC film (model MD-55-2) using fo
ur types of densitometers [He-Ne laser, broadband (white light) densit
ometer, and two LED (red-light) filtered densitometers] confirm the ac
curacy of this predictive model. The linearity and sensitivity of the
dose response curves are found to be highly dependent on the light sou
rce spectrum. Initial slope is a function of the average weighted abso
rbance. Early saturation and decreased linearity of the dose response
curves are ascribed to the nonuniform transmission of the light source
through the GC film. We found that an LED (red-light) source with a n
arrow bandpass filter centered at 671 nm near the major absorption pea
k achieves nearly the maximum possible sensitivity (almost four times
more sensitive than He-Ne laser, 632.8 nm) and may be suitable for in
vivo dosimetry. (C) 1997 American Association of Physicists in Medicin
e.