R. Yao et al., STUDY OF MULTISPECTRAL FRAME-BY-FRAME CONVOLUTION SCATTER CORRECTION IN HIGH-RESOLUTION PET, IEEE transactions on nuclear science, 44(6), 1997, pp. 2489-2493
High resolution PET scanners based on small individual detectors have
a low sensitivity resulting from increased inter-detector scatter. It
has been postulated that this limitation can be overcome by using enla
rged discrimination windows to include more low-energy events and by d
eveloping more efficient energy-dependent methods to correct for scatt
er. In this work, we investigate one such method based on the frame-by
-frame scatter correction of multispectral data. Images acquired in th
e conventional (344-658 keV), broad (129-658 keV) and multispectral (1
29-658 keV) window modes were processed by stationary and nonstationar
y convolution-restoration scatter correction methods. Broad and multis
pectral window acquisition improved counting efficiency relative to th
e conventional window. The degradation of image quality due to added s
catter can be mostly recovered by the subtraction-restoration scatter
correction. However, the multispectral frame-by-frame method was found
to be more sensitive to the effects of the nonstationary scatter resp
onse functions and its performance was not as good as that of the broa
d window. It is concluded that more sophisticated scatter degradation
models and correction methods need to be established to take full adva
ntage of multispectral data.