Two experiments examined the feasibility of psychological assessment u
sing interactive voice response (IVR) technology and the potential sen
sitivity of such assessments to alcohol and fatigue effects. In Experi
ment 1, 10 subjects performed a 12-min battery of six IVR-administered
tasks, Monday through Friday, over 2 weeks. Minimal learning effects
were evident during training. Repeated administrations indicated high
test-retest reliabilities. In Experiment 2 (double-blind, alcohol/plac
ebo crossover design), 7 subjects were tested every 2 h over a 24-h pe
riod during two experimental sessions (peak blood alcohol concentratio
ns = 80 mg/dL). Several NR-administered tasks were sensitive to alcoho
l impairment, but not as sensitive as laboratory-based measures specif
ically designed to assess alcohol impairment. Little evidence for fati
gue-related impairment was obtained. The results support optimism for
the potential to assess psychomotor and cognitive functioning distally
via telephony; however, further refinement and validation of the meth
ods are needed.