INTERACTION OF L-ASCORBIC-ACID WITH DL-N-METHYL-BETA-HYDROXYTRYPTAMINE

Authors
PREOBRAZHENSKAYA MN ROZHKOV II LAZHKO EI KOROLEV AM
Citation
Mn. Preobrazhenskaya et al., INTERACTION OF L-ASCORBIC-ACID WITH DL-N-METHYL-BETA-HYDROXYTRYPTAMINE, Tetrahedron letters, 39(1-2), 1998, pp. 109-112
Citations number
8
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
1-2
Year of publication
1998
Pages
109 - 112
Database
ISI
SICI code
0040-4039(1998)39:1-2<109:IOLWD>2.0.ZU;2-L
Abstract
The interaction of DL-N-methyl-beta-hydroxytryptamine 1 with L-ascorbi c acid 2 proceeds through the 2-C alkylation of 2 and the intramolecul ar acylation of the methylamino group to yield diastereomeric 1-methyl -3-(2,3,4-trihydroxybutyryl)pyrrolid-2-one 4a and 5b. (C) 1997 Elsevie r Science Ltd. All rights reserved.