DIASTEREOSELECTIVE FORMAL SYNTHESIS OF THE ANTIFUNGAL AGENT, (-PREUSSIN - A NEW ENTRY TO CHIRAL PYRROLIDINES())

Authors
DEARMAS P GARCIATELLADO F MARREROTELLADO JJ ROBLES J
Citation
P. Dearmas et al., DIASTEREOSELECTIVE FORMAL SYNTHESIS OF THE ANTIFUNGAL AGENT, (-PREUSSIN - A NEW ENTRY TO CHIRAL PYRROLIDINES()), Tetrahedron letters, 39(1-2), 1998, pp. 131-134
Citations number
18
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
1-2
Year of publication
1998
Pages
131 - 134
Database
ISI
SICI code
0040-4039(1998)39:1-2<131:DFSOTA>2.0.ZU;2-K
Abstract
A formal total synthesis of (+)-Preussin was achieved by using D-manno se as the starting material. The key step involved diastereoselective addition of allyltrimethylsilane to the bicyclic ketal 5. (C) 1997 Els evier Science Ltd. All rights reserved.