A NEW RADICAL ROUTE TO C4-UNSUBSTITUTED BETA-LACTAMS

Authors
ALCAIDE B RODRIGUEZVICENTE A SIERRA MA
Citation
B. Alcaide et al., A NEW RADICAL ROUTE TO C4-UNSUBSTITUTED BETA-LACTAMS, Tetrahedron letters, 39(1-2), 1998, pp. 163-166
Citations number
41
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
39
Issue
1-2
Year of publication
1998
Pages
163 - 166
Database
ISI
SICI code
0040-4039(1998)39:1-2<163:ANRRTC>2.0.ZU;2-B
Abstract
C4-Unsubstituted beta-lactams 3 are conveniently prepared from easily available 4-formyl-beta-lactams 1, in a sequential three step synthesi s, using as the key step a radical reductive decarbonylation of 4-carb oxy derivatives through their phenyl selenoesters 2. (C) 1997 Elsevier Science Ltd. All rights reserved.