Pneumonia is the second most common nosocomial infection in the United
States and the leading cause of death from nosocomial infections. Int
ubation and mechanical ventilation greatly increase the risk of bacter
ial pneumonia. Ventilator-associated pneumonia (VAP) occurs in a patie
nt treated with mechanical ventilation, and it is neither present nor
developing at the time of intubation; it is a serious problem-with sig
nificant morbidity and mortality rates. Aspiration of bacteria from th
e oropharynx, leakage of contaminated secretions around the endotrache
al tube, patient position, and cross-contamination from respiratory eq
uipment and health care providers are important factors in the develop
ment of VAP. Nurses caring for patients treated with mechanical ventil
ation must recognize risk factors and include strategies for reducing
these factors as part of their nursing care. This article summarizes t
he literature related to VAP: its incidence, associated factors, diagn
osis, and current therapies, with an emphasis on nursing implications
in the care of these patients.