NOVEL MONITORING STRATEGIES FOR XENOESTROGENS

The wide variety of known and unknown xenoestrogenic compounds require s intelligent solutions to detect polluted environmental samples and i dentify the structure and concentration of the relevant xenoestrogens. In this article, a summary is given of several methods that are at pr esent employed in the monitoring of xenoestrogens, Screening methods b ased on biological assays for the class-selective detection of xenoest rogens are reviewed, Furthermore, the analysis of known (xeno-)estroge ns is summarized. Novel interfaces between biological assays and chrom atography that facilitate the identification and quantification of xen oestrogens in complex samples are also discussed. (C) 1997 Elsevier Sc ience B.V.