GAUCHER-DISEASE - ASSESSMENT OF SKELETAL INVOLVEMENT AND THERAPEUTIC RESPONSES TO ENZYME REPLACEMENT

Authors
HERMANN G PASTORES GM ABDELWAHAB IF LORBERBOYM AM
Citation
G. Hermann et al., GAUCHER-DISEASE - ASSESSMENT OF SKELETAL INVOLVEMENT AND THERAPEUTIC RESPONSES TO ENZYME REPLACEMENT, Skeletal radiology, 26(12), 1997, pp. 687-696
Citations number
55
Journal title
Skeletal radiology → ACNP
ISSN journal
03642348
Volume
26
Issue
12
Year of publication
1997
Pages
687 - 696
Database
ISI
SICI code
0364-2348(1997)26:12<687:G-AOSI>2.0.ZU;2-C
Abstract
The clinical, pathological and radiological manifestations of type 1 G aucher disease and the role of imaging techniques such as CT, MRI and sulfur-colloid scintigraphy in the management of these patients is dis cussed. MRI appears to be the most valuable imaging technique for eval uating bone marrow involvement and detecting disease activity. MRI is also useful in assessing therapeutic responses to enzyme replacement t herapy.