CLINICAL MANIFESTATIONS OF LYME BORRELIOS IS IN THE MIDDLE URALS AND THEIR ASSOCIATIONS WITH GENETIC SPECIES OF BORRELIA-BURGDORFERI

A parallel study was made of the clinical spectrum of Lyme borreliosis in the Middle Urals and genetic species of the causative agent (Borre lia burgdorferi) in the ticks collected at the same territory. Clinica l picture of Lyme borreliosis ill the Middle Urals is different from t hat in America but had similar features with European borreliosis: ner vous disorders were more Frequent than arthritis, high incidence of th e symptoms ill segments close to the place of the agent inoculation, l ow occurrence of secondary erythema and carditis. The collected ricks were Ixodes persulcatus. They carried B. garinii, B. afzelii, VS116 ty pical for Europe. B. burgdorferi sensu stricto characteristic for USA where arthritis was mast common among tile symptoms was not detected. Thus, the findings confirm suggestions on association of Lyme borrelio sis clinical polymorphism in various geographic zones with genetic het erogeneity of the causative agent.