Ae. Karateev et al., ENDOSCOPIC ASSESSMENT OF RANITIDINE AND P IRENZEPINE EFFECTS ON GASTROPATHY CAUSED BY NONSTEROID ANTIINFLAMMATORY DRUGS, Terapevticeskij arhiv, 69(5), 1997, pp. 67-69
Two antiulcer drugs, ranitidine and pirenzepine belonging to blockers
of H-2-receptors and selective M-cholinoblockers, respectively, were c
ompared by efficacy against erosive and ulcer lesions in the upper gas
trointestinal mucosa. A total of 62 rheumatics were examined. In patie
nts treated by nonsteroid antiinflammatory drugs irrespectively of the
mode of their administration the highest response was shown by raniti
dine while pirenzepine efficacy proved poor.