MASS-SPECTROMETRY IN THE STUDY OF NONENZYMATIC GLYCO-OXIDATION OF PROTEINS

Authors
TRALDI P FAVRETTO D SERAGLIA R LAPOLLA A
Citation
P. Traldi et al., MASS-SPECTROMETRY IN THE STUDY OF NONENZYMATIC GLYCO-OXIDATION OF PROTEINS, Rapid communications in mass spectrometry, 11(6), 1997, pp. 673-678
Citations number
29
Categorie Soggetti
Spectroscopy,"Chemistry Analytical
Journal title
Rapid communications in mass spectrometry → ACNP
ISSN journal
09514198
Volume
11
Issue
6
Year of publication
1997
Pages
673 - 678
Database
ISI
SICI code
0951-4198(1997)11:6<673:MITSON>2.0.ZU;2-9
Abstract
Studies that have been performed by MALDI mass spectrometry in the fie ld of non-enzymatic protein glyco-oxidation are briefly reviewed. The results obtained by in vitro and in vivo experiments demonstrate the p ower of this technique, which is able to give information on the numbe r of sugar molecules condensed on specific proteins and, consequently, represents a new and specific diagnostic tool in diabetes control. (C ) 1997 by John Wiley & Sons, Ltd.