A. Frolich, COMBINED REPORTS ON SERUM-CALCIUM AND DISCRIMINANT FUNCTIONS INCREASETHE DIAGNOSTIC RATE OF HYPERCALCEMIA, Scandinavian journal of clinical & laboratory investigation, 57(8), 1997, pp. 725-729
Hypercalcaemia is a condition easily overlooked by the clinician. Prom
pted by the observation that computerized reminders could increase the
awareness, we have examined whether the combined reporting of increas
ed serum calcium results and the results from diagnostic discriminatin
g calculations could increase the clinical awareness of hypercalcaemia
. Albumin-corrected serum calcium was estimated in all 4500 patients a
dmitted to the hospital during a period of 2 months. Eighty-seven pati
ents were found with hypercalcaemia and were assigned randomly to 2 gr
oups: A (40 patients) and B (47 patients). In group A, the increased s
erum calcium and the results of the discriminant functions were report
ed; in group B, the serum calcium was reported only if requested and t
he discrimination diagnosis withheld. The clinical records were examin
ed 3 weeks after admission. At this time the records in group A contai
ned a relevant clinical diagnosis explaining the hypercalcaemia in 81%
of the cases. This was in contrast to only 31% of the records in grou
p B. We conclude that this combined reporting leads to a considerable
improvement in the clinical awareness of hypercalcaemia and results in
a diagnosis explaining the condition in the majority of cases.