Background. The role of laparoscopic intraoperative ultrasonography (I
OUS) in intraoperative decision making has grown rapidly in recent gea
rs. The purpose of this study was to evaluate its usefulness during la
paroscopic adrenalectomy. Methods. Since 1995, laparoscopic ultrasonog
raphy has been used to evaluate the adrenal gland and surrounding orga
ns in selective laparoscopic adrenalectomies. IOUS was performed in 19
of 114 laparoscopic adrenalectomies. Results. IOUS effected a change
in management in 68% of these patients. IOUS displayed the location of
the gland after a failed attempt at open resection; the adrenal vein,
expediting control in four operations; no extraadrenal involvement by
true large lesions (benign); vascular invasion in one tumor (carcinom
a), prompting open resection; periadrenal invasion by one metastatic c
ancer and lymph node involvement in another; a 7 mm hyperaldosteronoma
; no adenoma in two cases; bilateral hyperplasia; and a 14 cm cyst ori
ginating from the adrenal gland. IOUS facilitated partial adrenalectom
y in two patients and revealed centrally located adenomas in two other
s requiring total adrenalectomy. Conclusions. Laparoscopic IOUS during
adrenal operation is valuable in selected cases. It is helpful to loc
ate the gland and vein, confirm the presence or absence of abnormality
, discern the resectability of large masses, and facilitate a partial
adrenalectomy when desirable.