H. Akita et al., AN AMPHIPHILE-LIPASE AGGREGATE BEARING 1,2-DIALKYLATED MANNITOL ETHERAS A NEW-TYPE OF IMMOBILIZED ENZYME IN ORGANIC-SOLVENTS, Chemical and Pharmaceutical Bulletin, 45(12), 1997, pp. 2085-2088
Neutral amphiphiles of a nem type corresponding to 1,2-dialkylated man
nitol ethers (6-10) were synthesized, Amphiphile-lipase aggregates wer
e found to function as an immobilized enzyme system for enantioselecti
ve acetylation or enantioselective hydrolysis of alpha-hydroxy esters
or alpha-acetoxy esters, respectively, in organic solvents.