HLA-CW-ASTERISK-1602 - A NEW SUSCEPTIBILITY MARKER OF BEHCETS-DISEASEIN SOUTHERN SPAIN

Authors
SANZ L GONZALEZESCRIBANO F DEPABLO R NUNEZROLDAN A KREISLER M VILCHES C
Citation
L. Sanz et al., HLA-CW-ASTERISK-1602 - A NEW SUSCEPTIBILITY MARKER OF BEHCETS-DISEASEIN SOUTHERN SPAIN, Tissue antigens, 51(1), 1998, pp. 111-114
Citations number
18
Categorie Soggetti
Pathology,Immunology,"Cell Biology
Journal title
Tissue antigens → ACNP
ISSN journal
00012815
Volume
51
Issue
1
Year of publication
1998
Pages
111 - 114
Database
ISI
SICI code
0001-2815(1998)51:1<111:H-ANSM>2.0.ZU;2-T
Abstract
Genotyping of the HLA-C locus by PCR-SSP in Behcet's disease patients from southern Spain reveals a statistically significant association wi th Cw1602 (OR 20.15, corrected p < 0.05). This is an uncommon allele absent from the healthy control group, which seems to confer higher re lative risk than B51 in this study (OR 1.85), Stratified frequencies d o not show statistically significant differences but suggest that the Cw1602-B51 haplotype could be the main HLA marker of Behcet's disease in the analyzed population.