PHOTODISSOCIATION AND COLLISIONALLY ACTIVATED DISSOCIATION TANDEM MASS-SPECTROMETRIC STUDIES OF DIFLUORO[TRIAZOL-1-YLMETHYL]BENZHYDROLS ANDRELATED-COMPOUNDS IN A QUADRUPLE ION-TRAP

Photodissociation and collisionally activated dissociation have been u sed in conjunction with quadrupole ion trap tandem mass spectrometry. Visible (488.0 nm) and UV (333.6, 351.1, 363.8 nm) lines of a continuo us wave argon ion laser were employed in photodissociation experiments to investigate the effect of ion activation process and energy deposi tion on fragmentation. Flutriafol ([(RS)-2.4'-difluoro-(1H-1,2,4-triaz ol-1-yl methyl)benzhydrol)) and related structures were used as model compounds for collisional activation and UV/Vis photodissociation stud ies. All selected precursor ions were dissociated by collisional activ ation, but photodissociation shows dependence on the laser wavelength and the structure of the mass-selected precursor ion. In some cases, s eparate fragmentation pathways are accessed by CAD and PD activation p rocesses, yielding complementary structural information. (C) 1997 Else vier Science B.V.