M. Artico et al., BENIGN NEURAL SHEATH TUMORS OF MAJOR NERVES - CHARACTERISTICS IN 119 SURGICAL CASES, Acta neurochirurgica, 139(12), 1997, pp. 1108-1116
Peripheral benign nerve sheath tumours are infrequent tumours and affe
ct major nerve trunks, Some authors have indicated a high and prohibit
ive incidence of neurological injury in resection of these lesions. Th
e authors describe their findings in a retrospective study comprising
119 patients with spontaneous benign nerve sheath tumours of the perip
heral nervous system. Seventy-three patients had a schwannoma, 41 had
neurofibroma and 5 had plexiform neurofibroma: 25 of the 119 patients
suffered from neurofibromatosis, All schwannomas were excised complete
ly and the outcome of patients was 41.0% improved. 6.8% worsened, 52.0
% unchanged. Twenty-eight neurofibromas were excised completely and 13
subtotally; the outcome for patients was 19.5% improved, 19.5% worsen
ed and 61% unchanged. All plexiform neurofibromas were removed subtota
lly and the outcome for patients was 20% improved and 80% unchanged. T
he best surgical results at average follow-up of 6 years were observed
in the patients with schwannoma, the worst in those with plexiform ne
urofibroma. Our results demonstrated that it is often possible to remo
ve schwannomas as well as neurofibromas with an acceptable risk of inj
ury to the nerve.