Ma. Sebastiangambaro et al., INTRA-INDIVIDUAL AND INTERINDIVIDUAL BIOLOGICAL VARIABILITY DATA-BANK, European journal of clinical chemistry and clinical biochemistry, 35(11), 1997, pp. 845-852
Different results are usually observed when a quantity is measured in
different specimens from the same individual obtained over a time span
. For an individual, this variation is due to the imprecision of the m
easurement procedure, that is to say the metrological variability, as
well as to the rhythmic and random fluctuations of the quantity value
around a virtual homeostatic set point, that is to say the intra-indiv
idual biological variability. On the other hand, when studying the int
ra-individual biological variation of a quantity a mean value, the vir
tual homeostatic set point, is estimated for each individual participa
ting in the study. The variation among these mean values is due to the
inter-individual biological variability.