RAPID AND RELIABLE MEASUREMENT OF HIGHLY ELEVATED BLOOD AMMONIA CONCENTRATIONS IN CHILDREN

Authors
DEKEIJZER MH JAKOBS BS BRANDTS RW HOFS MTW TRIJBELS FJM SMEITINK JAM
Citation
Mh. Dekeijzer et al., RAPID AND RELIABLE MEASUREMENT OF HIGHLY ELEVATED BLOOD AMMONIA CONCENTRATIONS IN CHILDREN, European journal of clinical chemistry and clinical biochemistry, 35(11), 1997, pp. 853-854
Citations number
6
Journal title
European journal of clinical chemistry and clinical biochemistry → ACNP
ISSN journal
09394974
Volume
35
Issue
11
Year of publication
1997
Pages
853 - 854
Database
ISI
SICI code
0939-4974(1997)35:11<853:RARMOH>2.0.ZU;2-2
Abstract
Newborns and children may suffer:From extremely high ammonia levels in their blood. We evaluated a fast, reliable micromethod, based on the Blood Ammonia Checker II (BAG II) in combination with the dilution wit h fresh whole blood. Comparison of the proposed method with an enzymat ic method revealed a statistically significant correlation. We conclud e that the dilution of patient's blood with fresh whole blood extends the measuring range of ammonia on the BAC II analyzer from 286 mu mol/ l to about 700 mu mol/l.