P. Kim et al., BISEGMENTAL CERVICAL INTERBODY FUSION USING HYDROXYAPATITE IMPLANTS -SURGICAL RESULTS AND LONG-TERM OBSERVATION IN 70 CASES, Journal of neurosurgery, 88(1), 1998, pp. 21-27
Hydroxyapatite (HA) is the main constituent of bone mineral, and synth
etic HA serves as a biocompatible and bioactive material. It permits b
one growth on its surface and forms a union with the adjacent bone. Ob
ject. The authors have developed implants made of porous HA, which the
y have used in more than 90 cases in the past 6 years to achieve cervi
cal interbody fusion. The implants were designed to provide maximum du
rability, biomechanical stability, and alignment preservation and to b
e technically easy to use. The authors summarize their experience and
results with the use of these implants. Methods. The results of postop
erative follow-up observation of 12 months or longer (mean 37.1 +/- 2.
4 months) are available in 70 patients with underlying disease includi
ng: spondylosis, disc extrusion, ossification of the posterior longitu
dinal ligament (PLL), hypertrophy of the PLL, and trauma. The patients
' ages at the time of surgery ranged from 22 to 83 years (mean 50.6 +/
- 1.3 years). Flexion-extension radiographs and tomograms, obtained 6
and 12 months after surgery and every year thereafter, were used to de
monstrate solid fusion in all cases. Dislocation of the implant occurr
ed in three patients who were treated during the early portion of the
series. At 6 to 12 months after surgery, encasement of the implant and
formation of union were observed. Normal lordosis, if present prior t
o surgery, was maintained postsurgery. No neurological deterioration r
elated to the site of fusion occurred during the period of observation
. Conclusions. The authors conclude that satisfactory interbody fusion
can be achieved by using HA implants, provided their design is approp
riate and adequate surgical techniques are used.