MULTIPLE RADIATION-INDUCED INTRACRANIAL LESIONS AFTER TREATMENT FOR PITUITARY-ADENOMA - CASE-REPORT

This 53-year-old man presented with a syncopal episode 31 years after undergoing craniotomy and external-beam radiation for a pituitary macr oadenoma. A gadolinium-enhanced magnetic resonance (MR) image of the b rain demonstrated a 2.5-cm enhancing mass in the right caudate region that had not been seen on previous studies. A stereotactically guided biopsy procedure was performed to obtain specimens from the mass, whic h were consistent with ependymoma. The MR image also revealed two addi tional lesions that appeared to be within the radiation fields: a righ t temporal meningioma and a left frontal cavernous malformation. A rev iew of the literature found three previous reports in which ependymoma s presented after radiation therapy.