A disproportionately large number of the most important human food pla
nts is cyanogenic. The accumulated research of numerous people working
in several different disciplines now allows a tenable explanation for
this observation. Cyanogenesis by plants is not only a surprisingly e
ffective chemical defence against casual herbivores, but it is also ea
sily overcome by careful pre-ingestion food processing, this latter sk
ill being almost exclusive to humans. Moreover, humans have the physio
logical ability to detoxify cyanide satisfactorily, given an adequate
protein diet. It appears that early in the domestication of crop plant
s the cyanogenic species would have been relatively free of pests and
competitive herbivores, as well as having good nutritional qualities,
and thus ideal candidates for cultivation by the first farmers. (C) 19
97 Elsevier Science Ltd.