Four new ent-kaurenoids, leucophyllin A-D, were isolated from the aeri
al part of Rabdosia leuco-phylla. Their structures were elucidated on
the basis of spectroscopic and chemical evidence as ent-1 beta-hydroxy
-3 alpha,7 alpha,11 alpha- triacetoxykaur-16-en-6,15-dione, ent-1 beta
,11 alpha-dihydroxy-3 alpha,7 alpha-diacetoxykaur-16-en-6,15-dione,ent
- 1 beta,11 alpha,15 alpha-trihydroxy-3 alpha,7 alpha-diacetoxykaur-16
-en-6-one and ent-6 beta,11 alpha-dihydroxy-1 beta,3 alpha,7 alpha-tri
acetoxykaur- 16-en-15-one. The structure of leucophyllin C was also co
nfirmed by X-ray crystallographic analysis. (C) 1997 Elsevier Science
Ltd.