ACYLATED FLAVONOID GLYCOSIDES AND ACCOMPANYING PHENOLICS FROM LICORICE

Fifteen phenolic compounds including eight new flavonoid glycosides we re isolated from Tohoku licorice (a kind of commercial licorice, which is regarded as the underground part of Glycyrrhiza uralensis). The st ructures of the new compounds (3R)-vestitol 7-O-glucoside and acylated flavonoid glycosides (licorice-glycosides A, B, C1, C2, D1, D2 and E) , were elucidated. The H-1 NMR and CD spectral data of the acylated ch alcone apioglucosides suggested the existence of intramolecular stacki ng of the feruloyl or p-coumaroyl groups over the aglycone residue. (C ) 1997 Elsevier Science Ltd.