ANTIFUNGAL ALKALOIDS AND LIMONOID DERIVATIVES FROM DICTAMNUS-DASYCARPUS

From the root bark of Dictamnus dasycarpus (Rutaceae), four limonoid d erivatives, two furoquinoline alkaloids, five limonoids, two sesquiter penes and three steroids were isolated and their structures elucidated on the basis of various spectroscopic methods. Among the identified c ompounds, one was determined to be a new natural product, 6 beta-hydro xyfraxinellone, while six compounds were found to be active against th e plant pathogenic fungus Cladosporium cucumerinum. The relationship b etween the structures of limonoid derivatives and their inhibitory act ivity against fungal growth was investigated. (C) 1997 Elsevier Scienc e Ltd.