PYRROLIZIDINE ALKALOIDS FROM SENECIO-ROSEUS AND SENECIO-HELODES

Authors
PEREZCASTORENA AL ARCINIEGAS A CASTRO A VILLASENOR JL TOSCANO RA DEVIVAR AR
Citation
Al. Perezcastorena et al., PYRROLIZIDINE ALKALOIDS FROM SENECIO-ROSEUS AND SENECIO-HELODES, Journal of natural products, 60(12), 1997, pp. 1322-1325
Citations number
9
Categorie Soggetti
Chemistry Medicinal","Plant Sciences","Pharmacology & Pharmacy
Journal title
Journal of natural products → ACNP
ISSN journal
01633864
Volume
60
Issue
12
Year of publication
1997
Pages
1322 - 1325
Database
ISI
SICI code
0163-3864(1997)60:12<1322:PAFSAS>2.0.ZU;2-V
Abstract
Two new 13-membered macrocylic pyrrolizidine alkaloids, (13R)-13-hydro xyretroisosenine (2b) and (12S)-12-hydroxyretroisosenine (2c), have be en isolated from Senecio roseus and Senecio helodes. Their structures were established il om spectral and chemical studies including 2D NMR. The hydrochloride of retroisosenine (2a-HCl) was also isolated, and i ts absolute configuration was determined by X-ray diffraction analysis .