3-DIMENSIONAL MAXIMUM-QUANTUM CORRELATION HMQC NMR-SPECTROSCOPY (3D MAXY-HMQC)

The extension of two-dimensional maximum-quantum correlation spectrosc opy (2D MAXY NMR), which can be used to simplify complex NMR spectra, to three dimensions(3D) is described, A new pulse sequence for 3D MAXY -HMQC is presented and exemplified using the steroid drug dexamethason e. The sensitivity and coherence transfer efficiency of the MAXY NMR a pproach has also been assessed in relation to other HMQC- and HSQC-bas ed 3D methods. (C) 1997 Academic Press.