TYROSINE KINASE-ACTIVITY OF ROS AXONEME O F BULLS EYE

Authors
SHOLUKH AM BARANOVA LA ARTAMONOV ID VOLOTOVSKY ID
Citation
Am. Sholukh et al., TYROSINE KINASE-ACTIVITY OF ROS AXONEME O F BULLS EYE, Doklady Akademii nauk BSSR, 41(5), 1997, pp. 73-75
Citations number
12
Categorie Soggetti
Multidisciplinary Sciences
Journal title
Doklady Akademii nauk BSSR → ACNP
ISSN journal
0002354X
Volume
41
Issue
5
Year of publication
1997
Pages
73 - 75
Database
ISI
SICI code
0002-354X(1997)41:5<73:TKORAO>2.0.ZU;2-G
Abstract
The influence of metal ions, colchicine and vinblastine on ROS axoneme protein tyrosine kinase was studied. The optimal concentration of Mn2 + for the reaction is 5 mM; K-m values for ATP and poly(G,T)(n) are 4, 3 mu M and 31 mg/ml, respectively. Ca2+, colchicine and vinblastine we re shown to inhibit axoneme PTK.