T. Kishi et al., ALCOHOLIC MYOPATHY - EVALUATION WITH MAGNETIC-RESONANCE-IMAGING - A CASE-STUDY, Alcoholism, clinical and experimental research, 21(9), 1997, pp. 1730-1731
Magnetic resonance imaging (MRI) of thigh and leg muscles was performe
d in a patient viith alcoholic myopathy showing myalgia, hypercreatine
kinasemia, and hypermyoglobinemia. High signal intensities in both T-
1- and T-2-weighted images were widely distributed in the affected mus
cle groups, which most likely reflected lipid accumulation. Although h
e had hypermyoglobinemia, MRI and muscle biopsy did not show findings
of rhabdomyolysis, such as necrosis, regeneration, and edema, We sugge
st that the high signal intensities in this case may have indicated ''
prerhabdomyolysis'' related to alcohol abuse and that muscle MRI is us
eful in file evaluation of alcoholic myopathy, mainly predicting the o
nset of rhabdomyolysis.