SYNTHESIS OF OLIGO(5-AMINOPENTANOIC ACID)-NUCLEOBASES (APN) - POTENTIAL ANTISENSE AGENTS

Authors
BERGMEIER SC FUNDY SL
Citation
Sc. Bergmeier et Sl. Fundy, SYNTHESIS OF OLIGO(5-AMINOPENTANOIC ACID)-NUCLEOBASES (APN) - POTENTIAL ANTISENSE AGENTS, Bioorganic & medicinal chemistry letters, 7(24), 1997, pp. 3135-3138
Citations number
57
Journal title
Bioorganic & medicinal chemistry letters → ACNP
ISSN journal
0960894X
Volume
7
Issue
24
Year of publication
1997
Pages
3135 - 3138
Database
ISI
SICI code
0960-894X(1997)7:24<3135:SOOA(->2.0.ZU;2-T
Abstract
Oligomers of 5-amino pentanoic acid nucleobases have been prepared for use as antisense agents. The synthesis of the 5'-end starter unit and the 3'-end monomer unit, as well as the coupling procedures used for oligomer formation are described. (C) 1997 Elsevier Science Ltd.