Rl. Harter et al., A COMPARISON OF THE VOLUME AND ON OF GASTRIC CONTENTS OF OBESE AND LEAN SURGICAL PATIENTS, Anesthesia and analgesia, 86(1), 1998, pp. 147-152
Obese surgical patients are typically considered to be more Likely tha
n lean patients to possess high-volume and low-pH (HVLP) gastric conte
nts after a standard preoperative fast based on a study of a populatio
n predominately consisting of patients receiving intramuscular preoper
ative sedation. We revisited this issue in a study population of 256 f
asted surgical patients, of which 232 received no preoperative antacid
or gastric prokinetic drug. Immediately after endotracheal intubation
, an 18-French sump tube was placed, and gastric contents were withdra
wn. Subjects' gastric contents were defined as HVLP if they exhibited
a combination of a volume >25 mt and a pH <2.5. Obesity was defined as
a body mass index >30. Among nonmedicated obese patients, the proport
ion with HVLP gastric contents was 20 of 75 (26.6%). The proportion of
lean patients with HVLP gastric contents was 66 of 157 (42.0%). The d
ifference between the HVLP proportions for these two groups was found
to be significant (P < 0.05) using chi(2) analysis. Obesity seems to b
e associated with a significantly decreased risk of HVLP gastric conte
nts among surgical patients with no history of gastroesophageal pathol
ogy after a normal interval of preoperative fasting. Implications: Pre
vious studies have shown that obese surgical patients have a greater v
olume of acidic stomach contents than lean patients, despite a routine
preoperative fast. We have reexamined this issue and found that among
otherwise healthy, fasted, obese surgical patients, there is a lower
incidence of combined high-volume, low-pH stomach contents compared wi
th lean patients.