SERUM TOTAL, LDL, HDL CHOLESTEROL AND TRIGLYCERIDES RELATED TO AGE, GENDER AND CIGARETTE-SMOKING IN PATIENTS WITH FIRST ACUTE MYOCARDIAL-INFARCTION

The aim of this study was to examine relationships between total chole sterol, LDL, HDL cholesterol, triglycerides and age, gender; and cigar ette smoking in 190 patients (132 men and 58 women) aged 34-87 years w ith first AMI. The control group included 103 patients (57 men and 46 women) aged 29-90 years without a history of angina pectoris or AMI. H igh total cholesterol (over 5.2 mmol/L) was observed in 75% of patient s with AMI vs. 48% of patients in the control group (p < 0.001). Patie nts with AMI had significantly higher total cholesterol and LDL choles terol levels than controls (p < 0.0001). HDL cholesterol levels were s ignificantly Lower among patients with AMI than among the control grou p patients (p < 0.0001). Serum total cholesterol and LDL cholesterol i s higher in patients with AMI up to 60 years old, but lower in patient s older than 60 years. Women aged less than 50 years had significantly higher HDL cholesterol (p < 0.001), Lower LDL cholesterol (p < 0.001) , and lower total cholesterol (p < 0.05) than those over 50 years. Smo kers with AMI who smoked over 20 cigarettes per day had significantly higher total cholesterol, LDL cholesterol and triglycerides Levels tha n the non-smokers (p < 0.05). These findings suggest important influen ces of hyperlipoproteinemia and cigarette smoking upon development of myocardial infarction, especially in younger patients.