J. Djelmis et al., GLYCOSYLATED HEMOGLOBIN AND FETAL GROWTH IN NORMAL, GESTATIONAL AND INSULIN-DEPENDENT DIABETES-MELLITUS PREGNANCIES, Collegium antropologicum, 21(2), 1997, pp. 621-629
Aims of the study were: evaluation of HbA(1)c levels ir;, the peripher
al blood of pregnant women with insulin dependent diabetes, gestationa
l diabetes, glucose intolerance, and healthy pregnant controls; implic
ations of HbA(1)c concentration on detection and the control of women,
with impaired carbohydrate metabolism in pregnancy; comparison of HbA
(1)c levels with appearance of miscarriages, and premature deliveries;
comparison of weight gain during pregnancy to HbA(1)c levels; compari
son of difference from ideal body weight with HbA(1)c in diabetic preg
nant women; comparison of neonatal birth weight and HbA(1)c levels. 29
0 pregnant women were enrolled to the study. The highest value of HbA(
1)c teas in the group IDDM pregnant women (7.7% +/- 1.8%), and the low
est value of HbA(1)c was in the control group (4.1% +/- 0.5%). Statist
ically significant coefficients were found between HbA(1)c and weight
gain during pregnancy, between weight deviation from ideal body weight
and HbA(1)c (r = 0.54 and r = 0.48 respectively); and between, newbor
ns weight and HbA(1)c (r = 0.52). Well regulated glycemia and intensiv
e pregnancy follow-up of diabetic women reduces stillbirths, neonatal
complications and neonatal mucrosomia incidence.