Rotational atherectomy (Rotablation) represents one of the alternative
devices to treat complex coronary artery stenoses. Rather than increa
sing luminal diameter by arterial stretching and plaque fracture as wi
th balloon angioplasty, rotablation debulks atherosclerotic plaque wit
h an abrasive diamond coated bun. The basic physical principle is diff
erential cutting. It allows the advancing burr to selectively cut inel
astic material while elastic tissue deflects away from the bun: 95% of
the particles generated by the Rotablator are less than 5 microns. Th
ey are removed by the body's reticuloendothelial system. There are dif
ferent strategies to perform a rotablation, regarding the number of bu
rrs used and the final burr-to-artery ratio. An adjunctive PTCA is rec
ommended without proof by randomized studies so far. The best indicati
on for the Rotablator is the undilatable lesion. Lesion modification (
debulking) as a method of improving vessel compliance seems to be also
usefull in diffusely diseased and calcified vessels, as well as in ao
rto-ostial and angulated stenoses. The instent restenoses is a new ind
ication. Randomized studies will have to proof if there is an advantag
e for rotablation compared to PTCA. Restenosis rates appear comparable
to balloon angioplasty.